Duricef (Cefuroxime) – What It Is, How It Works, and When to Use It
If you’ve been prescribed Duricef, you probably wonder what the pill does and whether it’s right for you. Duricef is the brand name for cefuroxime, a second‑generation cephalosporin antibiotic. It kills bacteria by breaking down their cell walls, which stops the germs from growing and eventually wipes them out. Because it targets a broad range of bacteria, doctors often choose it for ear infections, sinus infections, pneumonia, and urinary tract infections.
When to Take Duricef
Duricef is usually taken twice a day, every 12 hours, with a full glass of water. Food can slow down its absorption, so it’s best to take it on an empty stomach unless your stomach is upset – then a small snack is fine. The exact dose depends on the infection type and how severe it is. For a typical adult with a sinus infection, the dose is 250 mg every 12 hours for 5‑10 days. Children get a weight‑based dose, so the doctor will calculate it carefully.
Never stop the pill early, even if you feel better. Stopping too soon can let some bacteria survive, which may cause the infection to come back and become resistant to antibiotics. If you miss a dose, take it as soon as you remember—unless it’s almost time for the next dose. In that case, skip the missed one and continue with your regular schedule. Don’t double‑up.
Possible Side Effects & Safety Tips
Most people tolerate Duricef well, but a few side effects are common. Stomach upset, diarrhea, and mild nausea happen in about one in ten users. If you get a rash, itching, or swelling of your face or lips, stop the medication and call your doctor right away—these could be signs of an allergic reaction.
Rarely, cefuroxime can affect blood clotting or cause a severe intestinal condition called Clostridioides difficile infection, which leads to watery diarrhea and abdominal pain. Seek medical help if you notice any sudden, severe symptoms.
Before you start Duricef, tell your doctor if you’re allergic to penicillin or other cephalosporins, have kidney problems, or are pregnant or breastfeeding. The drug is cleared by the kidneys, so people with reduced kidney function may need a lower dose.
To keep the medication safe, store it at room temperature away from moisture and heat. Keep the bottle tightly closed and out of reach of children.
Want a cheaper version? Generic cefuroxime tablets contain the same active ingredient and work just as well. Look for reputable online pharmacies that require a prescription and have clear contact information. Compare prices, read reviews, and verify the pharmacy’s licensing before you buy.
In summary, Duricef is a reliable choice for many bacterial infections when taken exactly as prescribed. Pay attention to the dosing schedule, watch for side effects, and talk to your doctor about any pre‑existing conditions. With the right use, you’ll beat the infection and get back to feeling normal quickly.

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